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Orangeburg, SC Area Online Reservations

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  1. Holiday Inn Santee
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    Resorts, Hotels & Motels, Reception Centers, Lodging

    Stay You. Experience the new look and feel of Holiday Inn. Book now.

    139 Bradford Blvd, Santee, SC (Map)

    Special Offer: Save up to 20% when you book early!

  2. Holiday Inn Express Hotel & Suites Orangeburg
    1 Review

    Luxury Hotels, Hotels & Motels, Reception Centers, Lodging

    Stay You. Experience the new look and feel of Holiday Inn Express. Book now.

    118 Sleep Inn Rd., Orangeburg, SC (Map)

    Special Offer: Save up to 20% when you book early!

  3. BEST WESTERN PLUS Santee Inn
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    Family-Friendly Hotels, Lodging, Event Planning

    I-95 Exit 98, Santee, SC (Map)

  4. Howard Johnson Express Inn - Orangeburg, SC
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    Family-Friendly Hotels, Boutique Hotels, Hotels & Motels

    3608 Saint Matthews Rd., Orangeburg, SC (Map)

  5. Sleep Inn
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    Family-Friendly Hotels, Business Hotels, Hotels & Motels

    3689 St. Matthews Rd, Orangeburg, SC (Map)

  6. Comfort Inn & Suites
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    Family-Friendly Hotels, Business Hotels, Budget Hotels

    3671 Saint Matthews Rd., Orangeburg, SC (Map)

  7. Best Western Orangeburg Inn & Suites
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    Family-Friendly Hotels, Lodging, Business Hotels

    746 Citadel Rd, Orangeburg, SC (Map)

  8. Quality Inn & Suites Downtown
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    Family-Friendly Hotels, Banquet Rooms, Business Hotels

    1415 John C Calhoun Dr, Orangeburg, SC (Map)

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