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Orangeburg, SC Area Business Hotels

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  1. Holiday Inn Express Hotel & Suites Orangeburg
    1 Review

    Luxury Hotels, Hotels & Motels, Reception Centers, Lodging

    Stay You. Experience the new look and feel of Holiday Inn Express. Book now.

    118 Sleep Inn Rd., Orangeburg, SC (Map)

    Special Offer: Save up to 20% when you book early!

  2. Quality Inn And Suites
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    Family-Friendly Hotels, Tourist Hotels, Business Hotels

    8929 Bass Dr, Santee, SC (Map)

  3. BEST WESTERN PLUS Santee Inn
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    Family-Friendly Hotels, Lodging, Event Planning

    I-95 Exit 98, Santee, SC (Map)

  4. Sleep Inn
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    Family-Friendly Hotels, Business Hotels, Hotels & Motels

    3689 St. Matthews Rd, Orangeburg, SC (Map)

  5. Quality Inn & Suites
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    Family-Friendly Hotels, Tourist Hotels, Business Hotels

    3671 Saint Matthews Rd, Orangeburg, SC (Map)

  6. Comfort Inn & Suites
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    Family-Friendly Hotels, Business Hotels, Budget Hotels

    3671 Saint Matthews Rd., Orangeburg, SC (Map)

  7. Best Western Orangeburg Inn & Suites
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    Family-Friendly Hotels, Lodging, Business Hotels

    746 Citadel Rd, Orangeburg, SC (Map)

  8. Quality Inn & Suites Downtown
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    Family-Friendly Hotels, Banquet Rooms, Business Hotels

    1415 John C Calhoun Dr, Orangeburg, SC (Map)

  9. Howard Johnson Express Inn - Orangeburg
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    Family-Friendly Hotels, Tourist Hotels, Business Hotels

    3608 Saint Matthews Rd, Orangeburg, SC (Map)

  10. Santee Inn & Suites
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    Family-Friendly Hotels, Resorts, Business Hotels

    221 Britain St, Santee, SC (Map)

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Orangeburg, SC Area Business Hotels

Citysearch helps you find Business Hotels in Orangeburg, SC Area. Check out our editors’ picks and user reviews to find the best affordable lodging near your destination. Got a recommendation for great Business Hotels in Orangeburg, SC Area? Write a review and tell us all about it.